Thyroid Disease and Autoimmune Thyroiditis
ثبت نشده
چکیده
Hypothyroidism is the most common endocrine disorder of canines, and up to 80% of cases result from autoimmune (lymphocytic) thyroiditis. The heritable nature of this disorder poses significant genetic implications for breeding stock. Thus, accurate diagnosis of the early compensatory stages of canine autoimmune thyroiditis leading up to hypothyroidism affords important genetic and clinical options for prompt intervention and case management.
منابع مشابه
Relationship between Anti-Thyroid Peroxidase Antibody and Thyroid Function Test
Background: Anti-thyroid peroxidase antibody (anti-TPO antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. Thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. Objective: To evaluate the relationship between serum levels of anti-TPO ...
متن کاملAutoimmune thyroiditis in benign and malignant thyroid nodules: 16-year results.
BACKGROUND It is controversial whether autoimmune thyroiditis is associated with higher frequency of papillary thyroid carcinoma (PTC). METHODS This was a cross-sectional, retrospective study. PTCs were compared to benign nodules regarding the prevalence of autoimmune thyroiditis over 16 years. RESULTS A similar proportion of autoimmune thyroiditis was observed in both benign and/or maligna...
متن کاملA Case Study of Silent Thyroiditis Associated with Idiopathic ُThrombocytopenic Purpura
A 48 Year-old woman had symptoms of thyrotoxicosis which disappeared spontaneously within two months. She was diagnosed as case of silent thyroiditis on the basis of both the clinical course and the laboratory data such as low uptake of radioactive Iodine and Technesium. She also had petechia in her arms which were diagnosed as an idiopathic thrombocytopenic purpura (I.T.P.). This case would se...
متن کاملThe role-playing autoantibodies in autoimmune thyroid diseases and their extra-thyroidal manifestations: review article
The presence of the antibodies against the main thyroid antigens, which include thyroid peroxidase (TPO) or microsomal antigen, thyroglobulin (Tg) as well as thyrotropin receptor or Thyroid Stimulating Hormone Receptor (TSH-R), is a hallmark and symbol of the autoimmune thyroid diseases (AITDs) as one of the most common autoimmune diseases (AD) around the world. The prevalence of the thyroid pe...
متن کاملInvariant NKT Cell Lines Derived from the NOD·H2h4 Mouse Enhance Autoimmune Thyroiditis
To study the role of invariant Natural Killer T cell ( iNKT) cells in autoimmune thyroiditis, we derived two iNKT cell lines from the spleens of NOD· H2(h4) mice, a strain that develops spontaneous autoimmune thyroiditis exacerbated by excess dietary iodine. The two lines were CD1d-restricted and expressed CD4(+), DX5(+), and the Vα4Jα281 gene segment, of the T-cell receptor α locus. Upon stimu...
متن کاملRadioiodine as a possible triggering agent for pemphigus foliaceus
Pemphigus foliaceus (PF) is an autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. PF has also been found in association with autoimmune diseases such as autoimmune thyroid disease (e.g. toxic nodular goiter and Hashimoto’s thyroiditis). In some patients, PF appears to be triggered by radioi...
متن کامل